Breast tumor surgery costs vary widely based on hospital and surgeon fees, insurance coverage, and additional treatments required. In the United States, a lumpectomy typically costs $10,000 to $20,000, while a mastectomy can cost $13,000 to $22,000. Surgery to remove the tumor or affected tissue can vary greatly based on the complexity and type of surgery (lumpectomy, mastectomy, or reconstructive surgery). The cost of surgery usually includes the surgeon's fee, hospital stay, and anesthesia, which together can total thousands to tens of thousands of dollars.